Advanced Gum Disease
Advanced gum disease (Periodontitis) is associated with extensive dental plaque formation dominated by anaerobic, gram-negative bacteria. Chronic inflammation results in the ulceration of the epithelium which allows bacteria to enter the gum tissue and the bloodstream. Inflamed gum tissue separates from teeth creating deep gum pockets in which the bacteria thrive. The body responds with even more chemical defenses. Aggressive synthesis of cytokines, C-reactive protein, lymphocytes and antibodies leads to the breakdown of collagen, the loss of supporting bone tissue and the subsequent loss of teeth.
